KPI-2 Antibody (H-9): sc-514237
- KPI-2 Antibody (H-9) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 78-99 near the N-terminus of KPI-2 of human origin
- recommended for detection of KPI-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KPI-2 Antibody (H-9) for WB applications. These reagents are now offered in bundles with KPI-2 Antibody (H-9) (see ordering information below).
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KPI-2 Antibody (H-9) is a mouse monoclonal IgG1 antibody that detects KPI-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KPI-2, also known as BREK, LMR2, cprk, AATYK2, or LMTK2 (lemur tyrosine kinase 2), is a 1,503 amino acid single-pass membrane protein that belongs to the protein kinase superfamily and the protein tyrosine kinase family. KPI-2 is primarily expressed in skeletal muscle, with weaker expression observed in the brain and pancreas. KPI-2 features N-terminal transmembrane helices and a long C-terminal cytoplasmic tail that exhibits serine/threonine/tyrosine kinase activity, which is crucial for various cellular processes. KPI-2 is involved in nerve growth factor (NGF)-TrkA signaling, endosomal membrane trafficking, and spermatogenesis, highlighting KPI-2′s importance in cellular communication and development. KPI-2′s localization to cytoplasmic membrane vesicles and perinuclear recycling endosomes is essential for the transition of endocytosed membrane vesicles from early endosomes to recycling endosomes, a process vital for maintaining cellular homeostasis and function. Furthermore, the gene encoding KPI-2 has emerged as a potential therapeutic target for prostate cancer, making anti-KPI-2 antibody (H-9) a valuable tool for researchers investigating KPI-2′s role in cancer biology and other physiological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KPI-2 Antibody (H-9) | sc-514237 | 200 µg/ml | $322.00 | |||
KPI-2 Antibody (H-9): m-IgG Fc BP-HRP Bundle | sc-538605 | 200 µg Ab; 10 µg BP | $361.00 | |||
KPI-2 Antibody (H-9): m-IgGκ BP-HRP Bundle | sc-536249 | 200 µg Ab; 40 µg BP | $361.00 | |||
KPI-2 Antibody (H-9): m-IgG1 BP-HRP Bundle | sc-545792 | 200 µg Ab; 20 µg BP | $361.00 | |||
KPI-2 (H-9) Neutralizing Peptide | sc-514237 P | 100 µg/0.5 ml | $69.00 |