KIF27 Antibody (A-9): sc-390766

KIF27 Antibody (A-9) is a mouse monoclonal IgM antibody that detects KIF27 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-KIF27 antibody (A-9) is available as the non-conjugated form. KIF27, or kinesin family member 27, is a vital motor protein composed of 1401 amino acids, featuring a kinesin-motor domain that facilitates ATP-dependent movement along microtubules. KIF27 plays a significant role in intracellular transport, particularly in the distribution of organelles and vesicles, which is crucial for maintaining cellular organization and function. KIF27 is also implicated in essential processes such as cell division and membrane trafficking, including endocytosis and transcytosis, highlighting its importance in cellular dynamics. The gene encoding human KIF27 is located on chromosome 9, a region associated with various genetic disorders, including hereditary hemorrhagic telangiectasia and familial dysautonomia. Understanding the function and mechanisms of KIF27 is essential for elucidating its role in health and disease, particularly in the context of cellular transport and organization.

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KIF27 Antibody (A-9) References:

1. All kinesin superfamily protein, KIF, genes in mouse and human.  |  Miki, H., et al. 2001. Proc Natl Acad Sci U S A. 98: 7004-11. PMID: 11416179
2. A kinesin medley: biochemical and functional heterogeneity.  |  Brady, ST. 1995. Trends Cell Biol. 5: 159-64. PMID: 14732151
3. DNA sequence and analysis of human chromosome 9.  |  Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
4. Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia.  |  Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
5. Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia.  |  Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
6. Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia.  |  Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996
7. The emerging kinesin family of microtubule motor proteins.  |  Endow, SA. 1991. Trends Biochem Sci. 16: 221-5. PMID: 1832505
8. Motor proteins of cytoplasmic microtubules.  |  Vallee, RB. and Shpetner, HS. 1990. Annu Rev Biochem. 59: 909-32. PMID: 2142876

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-KIF27 Antibody (A-9) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-KIF27 Antibody (A-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

KIF27 Antibody (A-9) Specifications

Alternate Product Name: KIF27

Product Clone Name: A-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 617-644

Epitope Target: KIF27

Epitope Species: human

Product Reactivity/Detection: KIF27

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for KIF27 Antibody (A-9): P: Blocking Peptide