Hep A VP3 Antibody (1881): sc-58140
- Hep A VP3 Antibody (1881) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against Hep A
- recommended for detection of nuetralizing epitope of VP3 of Hep A origin by IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Hep A VP3 Antibody (1881). This work is in progress.
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Hep A VP3 Antibody (1881) is a mouse monoclonal IgG1 antibody that detects Hep A VP3 protein of Hepatitis A virus by immunofluorescence (IF) and enzyme-linked immunosorbent assay (ELISA). Hep A VP3 is a crucial capsid protein that plays a significant role in the virus′s life cycle, as Hep A VP3 is involved in the assembly and stability of the viral capsid, which is essential for the virus′s ability to infect host cells. The presence of an amino terminal T cell epitope within Hep A VP3 is particularly important, as Hep A VP3 can elicit an immune response, potentially aiding in the development of vaccines and therapeutic strategies against Hepatitis A. Additionally, Hep A VP3′s ability to couple with liposomes suggests involvement in cellular interactions that may influence viral entry and propagation. Understanding Hep A VP3 function is vital for elucidating the mechanisms of Hepatitis A infection and for developing effective interventions.
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Hep A VP3 Antibody (1881) References:
- pH-induced destabilization of lipid bilayers by a peptide from the VP3 protein of the capsid of hepatitis A virus. | Chávez, A., et al. 1998. Analyst. 123: 2251-6. PMID: 10396798
- Hepatitis A Synthetic Peptide VP3(110-121) Miscibility with Dipalmitoylphosphatidylcholine, Dipalmitoylphosphatidylglycerol, and Stearylamine Monolayers. | Sospedra, P., et al. 2000. J Colloid Interface Sci. 221: 230-235. PMID: 10631024
- Effect of chain length of HAV-VP3 synthetic peptides on its interaction with biomembrane models. | Sospedra, P., et al. 2000. Biopolymers. 54: 477-88. PMID: 10984400
- Hepatitis A virus VP3 may activate serum response element associated transcription. | Kanda, T., et al. 2003. Scand J Gastroenterol. 38: 307-13. PMID: 12737447
- The covalent coupling of HAV-VP3 (110-121) synthetic peptide to liposomes: physicochemical studies. | Muñoz, M., et al. 2004. Int J Pharm. 269: 177-84. PMID: 14698589
- Structure of the hepatitis A virion: peptide mapping of the capsid region. | Wheeler, CM., et al. 1986. J Virol. 58: 307-13. PMID: 3009847
- Prognostic, clinical, and therapeutic importance of RANTES-CCR5 axis in hepatitis A infection: A multiapproach study. | Baruah, V., et al. 2021. J Med Virol. 93: 3656-3665. PMID: 32975838
- Synthesis, lipophilic derivatization and interaction with liposomes of HAV-VP3 (102-121) sequence by using spectroscopic techniques. | Garcia, M., et al. 1996. Analyst. 121: 1583-8. PMID: 8952449
- Conformational behavior of the HAV-VP3(110-121) peptidic sequence and synthetic analogs in membrane environments studied by CD and computational methods. | Pérez, JA., et al. 1998. Biopolymers. 45: 479-92. PMID: 9577229
- Enhancement of the immunogenicity of a synthetic peptide bearing a VP3 epitope of hepatitis A virus. | Pintó, RM., et al. 1998. FEBS Lett. 438: 106-10. PMID: 9821968
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hep A VP3 Antibody (1881) | sc-58140 | 100 µg/ml | $322.00 |