Headpin Antibody (A-5): sc-393307
- Headpin Antibody (A-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 260-279 within an internal region of Headpin of rat origin
- recommended for detection of Headpin of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Headpin Antibody (A-5) for WB applications. These reagents are now offered in bundles with Headpin Antibody (A-5) (see ordering information below).
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SEE ALSO...
Headpin Antibody (A-5) is a mouse monoclonal IgG1 antibody that detects Headpin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Headpin, also known as hurpin or serpinB13, is a skin-specific serine proteinase inhibitor that plays a crucial role in regulating proteolytic activity in the epidermis, which is essential for maintaining skin homeostasis and protecting against environmental stressors, including UV radiation. Headpin′s function is underscored by abundant expression in human keratinocyte cell lines, such as HaCaT, and presence in lesional keratinocytes from psoriatic skin, where Headpin may contribute to the pathophysiology of skin disorders. Notably, downregulation of Headpin has been observed in squamous cell carcinoma of the oral cavity and in squamous cell carcinoma cell lines from the head and neck, indicating Headpin′s potential role as a biomarker for cancer progression and a target for therapeutic intervention. With versatile applications and significant biological relevance, anti-Headpin antibody (A-5) serves as an invaluable tool for researchers investigating skin biology and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Headpin Antibody (A-5) | sc-393307 | 200 µg/ml | $322.00 | |||
Headpin Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-538185 | 200 µg Ab; 10 µg BP | $361.00 | |||
Headpin Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-535748 | 200 µg Ab; 40 µg BP | $361.00 | |||
Headpin Antibody (A-5): m-IgG1 BP-HRP Bundle | sc-545563 | 200 µg Ab; 20 µg BP | $361.00 | |||
Headpin (A-5) Neutralizing Peptide | sc-393307 P | 100 µg/0.5 ml | $69.00 |