Filensin Antibody (C3PO): sc-69691

Filensin Antibody (C3PO) is a mouse monoclonal IgG1 antibody that detects Filensin in bovine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Filensin, also known as CP94, CP95, or CP97, is a vital cytoskeletal intermediate filament protein found in the eye lens, where anti-Filensin antibody (C3PO) plays a crucial role in studying beaded filaments that maintain optical clarity over time. Filensin is essential for lens development, regulating the shape and conformation of lens fiber cells, thereby ensuring lens transparency. The structure of Filensin includes a C-terminal non-α-helical domain that is integral to function, while the head domain features a di-arginine/aromatic amino acid motif that harbors a potential phosphorylation site for protein kinase A, highlighting Filensin′s importance in cellular signaling pathways. Filensin monoclonal antibody (C3PO) serves as an invaluable tool for researchers studying lens biology and related disorders, providing insights into the molecular mechanisms that underpin lens fiber cell integrity and function.

The preferred Filensin antibody is Filensin Antibody (IB38): sc-69689.