Fibronectin Antibody (IST-9): sc-59826

Fibronectin Antibody (IST-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects Fibronectin in mouse, rat, human, porcine, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Fibronectin antibody (IST-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Fibronectin is a crucial extracellular matrix glycoprotein that plays a significant role in cell adhesion, motility, and wound healing, making Fibronectin vital for tissue repair and regeneration. This high molecular weight heterodimeric protein is predominantly located on cell surfaces, in extracellular fluids, and in plasma, where Fibronectin facilitates interactions between cells and the extracellular matrix. Alternative splicing and glycosylation of Fibronectin lead to the generation of various isoforms, some of which are associated with specific tissues or pathological conditions, such as malignancies. The presence of glycosylated Fibronectin and Fibronectin splice variants has been linked to the formation of the myofibroblast phenotype in Dupuytren′s disease, highlighting the importance of understanding post-translational modifications in disease contexts.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Fibronectin Antibody (IST-9) has 81 citations in a variety of scientific publications.

Primary antibodies like Anti-Fibronectin Antibody (IST-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Fibronectin Antibody (IST-9) Specifications

Alternate Product Name: Fibronectin

Product Clone Name: IST-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: cellular Fibronectin

Epitope Species: human

Product Reactivity/Detection: cellular Fibronectin

Species Reactivity/Detection: mouse, rat, human, porcine, canine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 81 citations in various scientific publications

Available Conjugates/Forms for Fibronectin Antibody (IST-9): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Fibronectin antibody is Fibronectin Antibody (EP5): sc-8422.