Feprazone CAS: 30748-29-9
MF: C20H20N2O2
MW: 320.38
Inducer of the P-450 2B family of cytochromes.

Feprazone (CAS 30748-29-9)

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Applicazione: Feprazone is inducer of the P-450 2B family of cytochromes
Numero CAS: 30748-29-9
Peso molecolare: 320.38
Formula molecolare: C20H20N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Feprazone is a non-steroidal, anti-inflammatory compound. Feprazone is noted to be structurally similar to phenylbutazone (sc-204843; deuterium-labelled sc-219696) and has been utilized in research studies analyzing the induction of cytochrome P-450. Feprazon was also reported to induce the P450 2B family of cytochromes. Metabolization of Feprazone by CYP2B is reported to occur at two positons on the side chains of the compound through a molecular modeling of the interaction of the Feprazon and mammalian CYP2B.


Referenze

1. Smith, J.N., et al. 1990. J. Biochem. Toxicol. 5: 9-12. PMID: 2402005
2. Lewis, D.F. and Lake, B.G. 1997. Xenobiotica. 27: 443-478. PMID: 9179987

Aspetto :
Powder
Stato fisico :
Solid
Solubilità :
Soluble in chloroform, acetone, DMF, methanol (slightly), and ethanol (slightly).
CONSERVAZIONE :
Store at 4° C
Punto di scioglimento :
156.5° C
Punto di ebollizione :
437.20° C
Densità :
1.18 g/cm3
Indice di rifrazione :
n20D 1.6
Valori pK :
pKa: 4.06 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
Numero MDL :
MFCD00866063
Numero EC :
250-324-3
Registro Beilstein :
3984862
SMILES :
CC(=CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)C

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CERTIFICATO DI ANALISI

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