Endoglin/CD105 Antibody (2Q1707): sc-71042
- Endoglin/CD105 Antibody (2Q1707) is a rat monoclonal IgG2a, cited in 17 publications, provided at 200 µg/ml
- raised against inflamed mouse skin tissue
- recommended for detection of Endoglin of mouse, rat and human origin by WB, IP, IF and FCM
- See Endoglin/CD105 (P3D1): sc-18838 for Endoglin/CD105 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Endoglin/CD105 Antibody (2Q1707). This work is in progress.
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Endoglin Antibody (2Q1707) is a rat monoclonal IgG2a antibody that recognizes Endoglin in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-Endoglin antibody (2Q1707) targets a co-receptor for transforming growth factor-beta (TGF-β) superfamily ligands, which regulate endothelial cell proliferation, migration, and differentiation, playing a crucial role in vascular development and homeostasis. Endoglin (2Q1707) monoclonal antibody helps researchers understand hereditary hemorrhagic telangiectasia (HHT), a genetic disorder where mutations in Endoglin disrupt normal blood vessel formation, leading to hemorrhages and ischemia. Endoglin (2Q1707) antibody enables studies of vascular endothelial cells, supporting research in vascular biology, endothelial function, and vascular disorder pathogenesis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Endoglin/CD105 Antibody (2Q1707) References:
- CD105 (endoglin) expression on hematopoietic stem/progenitor cells. | Pierelli, L., et al. 2001. Leuk Lymphoma. 42: 1195-206. PMID: 11911400
- Soluble endoglin is an accurate predictor and a pathogenic molecule in pre-eclampsia. | López-Novoa, JM. 2007. Nephrol Dial Transplant. 22: 712-4. PMID: 17210583
- Endoglin as a marker in cervical paragangliomas. | Eleno, N., et al. 2010. Head Neck. 32: 737-43. PMID: 19827102
- A systematic review of endoglin gene expression in preeclampsia. | Bell, MJ. and Conley, YP. 2013. Biol Res Nurs. 15: 129-36. PMID: 21921088
- Membrane and soluble forms of endoglin in preeclampsia. | Oujo, B., et al. 2013. Curr Mol Med. 13: 1345-57. PMID: 23826920
- Endoglin overexpression mediates gastric cancer peritoneal dissemination by inducing mesothelial cell senescence. | Miao, ZF., et al. 2016. Hum Pathol. 51: 114-23. PMID: 27067789
- Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis. | Paauwe, M., et al. 2018. Clin Cancer Res. 24: 6331-6344. PMID: 29945992
- ALK1 regulates the internalization of endoglin and the type III TGF-β receptor. | Tazat, K., et al. 2021. Mol Biol Cell. 32: 605-621. PMID: 33566682
- High Soluble Endoglin Levels Affect Aortic Vascular Function during Mice Aging. | Nejmanová, I., et al. 2021. J Cardiovasc Dev Dis. 8: PMID: 34940528
- Endoglin (CD105) and proliferation index in recurrent glioblastoma treated with anti-angiogenic therapy. | Bastos, AGP., et al. 2022. Front Oncol. 12: 910196. PMID: 36147918
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Endoglin/CD105 Antibody (2Q1707) | sc-71042 | 200 µg/ml | $322.00 |