E-cadherin Antibody (Sec11): sc-59780
- E-cadherin Antibody (Sec11) is a mouse monoclonal IgG1, cited in 5 publications, provided at 100 µg/ml
- raised against amino acids 9-21 of E-cadherin of human origin
- recommended for detection of both the 120 kDa E-cadherin and the 80 kDa Trypsin-resistant extracellular part of mouse, rat, human and canine origin by WBIP
- See E-cadherin (G-10): sc-8426 for E-cadherin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for E-cadherin Antibody (Sec11). This work is in progress.
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SEE ALSO...
E-cadherin Antibody (Sec11) is a mouse monoclonal IgG1 antibody that detects E-cadherin in mouse, rat, human, and canine samples through applications such as western blotting (WB) and immunoprecipitation (IP). E-cadherin plays a crucial role in maintaining cell-cell adhesion, which is essential for the integrity of epithelial tissues and the regulation of morphogenetic processes. E-cadherin is primarily located at the cell membrane, where E-cadherin forms adherens junctions that connect adjacent cells, thereby contributing to tissue architecture and stability. Proper functioning of E-cadherin is vital for preventing the epithelial-to-mesenchymal transition, a process that can lead to increased cell motility and is often implicated in cancer metastasis. E-cadherin′s extracellular domain is characterized by a series of five homologous repeats that facilitate binding to other cadherins and cytoplasmic proteins, such as β-catenin, which are essential for signal transduction and maintaining cellular cohesion. Anti-E-cadherin antibody (Sec11) is an invaluable tool for researchers studying cell adhesion mechanisms, tissue development, and the pathological processes associated with cancer progression.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
E-cadherin Antibody (Sec11) | sc-59780 | 100 µg/ml | $322.00 |