DJ-1 Antibody (A-9): sc-55573

DJ-1 Antibody (A-9) is a mouse monoclonal IgG antibody that detects DJ-1 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). DJ-1 is a highly-conserved protein that plays a crucial role in cellular processes, particularly in protecting cells from oxidative stress and maintaining mitochondrial function. DJ-1′s ability to regulate the androgen receptor by forming a complex with PIASxα highlights DJ-1′s importance in hormonal signaling pathways, which can have significant implications in both cancer biology and neurodegenerative diseases. The gene encoding DJ-1 is located on chromosome 1p36.23, a region associated with various chromosomal abnormalities in tumor cells, and mutations in this gene have been linked to Parkinson′s disease, underscoring DJ-1′s relevance in neuroprotection. DJ-1 is ubiquitously expressed and translocates from the cytoplasm to the nucleus during the S phase of the cell cycle, indicating DJ-1′s dynamic role in cellular responses to growth stimuli. With multifaceted functions and implications in disease, anti-DJ-1 antibody (A-9) serves as an essential tool for researchers investigating the molecular mechanisms underlying various pathologies.

The preferred DJ-1 antibody is DJ-1 Antibody (D-4): sc-55572.