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Cytokeratin 18 Antibody (2X44) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 18 in human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Cytokeratin 18 is a vital component of the cytoskeleton in epithelial cells, contributing significantly to structural integrity and resilience. Cytokeratin 18 is predominantly located in the cytoplasm, forming a network of intermediate filaments that provide mechanical support and shape to cells. Proper localization of Cytokeratin 18 is crucial for maintaining epithelial tissue architecture, and disruption can lead to various pathological conditions, including cancer. Cytokeratin 18 serves as a biomarker for epithelial-derived tumors, as expression levels can indicate differentiation status of malignant cells. Post-translational modifications of Cytokeratin 18, such as phosphorylation, can influence interactions with other proteins and overall function within cells. Anti-Cytokeratin 18 antibody (2X44) enables researchers to explore epithelial biology and cancer pathology, advancing understanding of this protein′s role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 18 Antibody (2X44) | sc-70917 | 200 µg/ml | $322.00 | |||
Cytokeratin 18 Antibody (2X44): m-IgG Fc BP-HRP Bundle | sc-539322 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cytokeratin 18 Antibody (2X44): m-IgG1 BP-HRP Bundle | sc-541408 | 200 µg Ab; 20 µg BP | $361.00 | |||
Cytokeratin 18 Antibody (2X44) FITC | sc-70917 FITC | 200 µg/ml | $336.00 | |||
Cytokeratin 18 Antibody (2X44) PE | sc-70917 PE | 200 µg/ml | $349.00 |