CTNNBL1 Antibody (D-2): sc-398335

CTNNBL1 Antibody (D-2) is a mouse monoclonal IgG1 antibody that detects CTNNBL1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CTNNBL1, also known as nuclear-associated protein (NAP) or P14L, is an evolutionarily conserved protein that shares structural similarities with members of the armadillo family, including β-catenin. CTNNBL1 is predominantly localized in the nucleus, where CTNNBL1 plays a crucial role in various cellular processes, including apoptosis, due to its C-terminal domain. The presence of a bipartite nuclear localization signal, along with multiple phosphorylation sites, underscores CTNNBL1′s importance in regulating gene expression and cellular signaling pathways. Notably, CTNNBL1 has been implicated in metabolic processes, as several single nucleotide polymorphisms (SNPs) associated with CTNNBL1 have been linked to fat mass and body mass index (BMI), highlighting CTNNBL1′s potential role in obesity development. With diverse functions and significant implications in health and disease, anti-CTNNBL1 antibody (D-2) is an essential tool for researchers investigating the molecular mechanisms underlying these processes.

The preferred CTNNBL1 antibody is CTNNBL1 Antibody (A-5): sc-376847.