Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CLEC-2 (C-type lectin-like receptor 2), also referred to as C-type lectin domain family 1 member B, is a monomeric, single pass, type II membrane protein belonging to a non-classical C-type lectin class of platelet activating receptors. It is expressed on the surface of platelets, immune cells of myeloid origin and in liver. C-type lectin receptors play important roles in pathogen recognition within the immune system. CLEC-2 acts as a receptor for the snake venom protein, rhodocytin. It also acts as a co-receptor for HIV-1, promoting virus capture by cells and platelets. Activation of CLEC-2 involves the tyrosine phosphorylation of its cytoplasmic tail. It signals by the activation of PLCγ2 through Src and Syk dependent pathways which lead to platelet activation and aggregation. In addition, CLEC-2 interacts with podoplanin, a sialoglycoprotein, and together they may regulate tumor growth and play a role in the formation of lymphatic vessels.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
How much sample do you recommend loading on the gel for Western blot detection using CLEC-2 (53Ex9): sc-73851?
Richiesta da: jerojero
We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference.
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