CKR-8 Antibody (Z-12): sc-73847
- CKR-8 Antibody (Z-12) is a rat monoclonal IgG2b provided at 100 µg/ml
- raised against BaF/3 cells transfected with CKR-8 of human origin
- recommended for detection of CKR-8 of human origin by FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CKR-8 Antibody (Z-12). This work is in progress.
CKR-8 Antibody (Z-12) is a rat monoclonal IgG2b antibody that detects CKR-8 in human samples through flow cytometry (FCM). CKR-8, also known as chemokine receptor 8, plays a crucial role in the immune system by mediating the activation, migration, and proliferation of lymphoid cells, particularly monocytes and type 2 T lymphocytes. CKR-8 is predominantly expressed in lymphoid tissues such as the thymus, spleen, and lymph nodes, where CKR-8 responds to specific chemokines like I-309 and monocyte inflammatory protein-1 (vMIP-I). Anti-CKR-8 antibody (Z-12) facilitates the chemotaxis of immune cells to sites of inflammation, thereby contributing to the body′s defense mechanisms. CKR-8′s interaction with its ligands is essential for proper functioning of the immune response, particularly in regulating the movement of T lymphocytes, which are vital for adaptive immunity. CKR-8 (Z-12) antibody serves as an invaluable tool for researchers studying immune cell dynamics and the underlying mechanisms of inflammation and immune responses in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CKR-8 Antibody (Z-12) | sc-73847 | 100 µg/ml | $322.00 |