Anticorpo Annexin III (E-11): sc-390502

Annexin III Antibody (E-11) is an IgG_2a κ mouse monoclonal Annexin III antibody (also designated ANXA3 antibody, Annexin A3 antibody, 35-alpha calcimedin antibody, Lipocortin III antibody or Placental anticoagulant protein III antibody) suitable for the detection of the Annexin III protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Annexin III Antibody (E-11) is available as both the non-conjugated anti-Annexin III antibody form, as well as multiple conjugated forms of anti-Annexin III antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor^® conjugates. The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-α calcimedin or ANX3, belongs to the annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.

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