Date published: 2026-4-24

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3-Methylcrotonyl Glycine (CAS 33008-07-0)

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Alternate Names:
2-(3-methylbut-2-enoylamino)acetic acid; N-(3-Methyl-1-oxo-2-butenyl)glycine
Application:
3-Methylcrotonyl Glycine is A metabolite found in 3-methylcrotonylglycinuria
CAS Number:
33008-07-0
Purity:
≥95%
Molecular Weight:
157.17
Molecular Formula:
C7H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Methylcrotonyl Glycine is a compound of interest in the study of organic chemistry and metabolism. It is often examined in the context of amino acid catabolism and the leucine degradation pathway. Researchers use 3-Methylcrotonyl Glycine to investigate enzyme deficiencies, particularly those related to the metabolism of branched-chain amino acids. Additionally, this compound is relevant in the study of inborn errors of metabolism, serving as a biomarker for specific genetic conditions. In analytical chemistry, 3-Methylcrotonyl Glycine is used as a standard for mass spectrometry and chromatography to identify and quantify metabolites in biological samples. Its role in the broader metabolic network is also a subject of research, contributing to the understanding of cellular bioenergetics and nutrient utilization.


3-Methylcrotonyl Glycine (CAS 33008-07-0) References

  1. N-acylglycine amidation: implications for the biosynthesis of fatty acid primary amides.  |  Wilcox, BJ., et al. 1999. Biochemistry. 38: 3235-45. PMID: 10079066
  2. Reaction of alkaline sodium picrate with creatinine: I. Kinetics and mechanism of formation of the mono-creatinine picric acid complex.  |  Vasiliades, J. 1976. Clin Chem. 22: 1664-71. PMID: 10095
  3. Molecular mechanism of dominant expression in 3-methylcrotonyl-CoA carboxylase deficiency.  |  Baumgartner, MR. 2005. J Inherit Metab Dis. 28: 301-9. PMID: 15868465
  4. [Follow up and gene mutation analysis in cases suspected as 3-methylcrotonyl-coenzyme A carboxylase deficiency by neonatal screening].  |  Ye, J., et al. 2014. Zhonghua Er Ke Za Zhi. 52: 409-14. PMID: 25190158
  5. The enzymes of mitochondrial fatty acid oxidation.  |  Bennett, MJ. 1994. Clin Chim Acta. 226: 211-24. PMID: 7923814
  6. Effect of treatment with glycine and L-carnitine in medium-chain acyl-coenzyme A dehydrogenase deficiency.  |  Rinaldo, P., et al. 1993. J Pediatr. 122: 580-4. PMID: 8463904

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Methylcrotonyl Glycine, 1 mg

sc-209651
1 mg
$162.00

3-Methylcrotonyl Glycine, 5 mg

sc-209651A
5 mg
$290.00