1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine (CAS 3922-61-0)

1,2-Dipalmitoyl-sn-glycero-3-phospho(N-palmitoyl)ethanolamine ammonium salt, often referred to as DPPC-PE, is a synthetic phospholipid extensively used in biophysical research for its ability to form stable, robust lipid bilayers that closely mimic the outer leaflet of mammalian plasma membranes. This compound comprises two palmitoyl chains attached to the sn-glycerol backbone, with an additional palmitoyl group linked to a phosphoethanolamine headgroup, and an ammonium salt to enhance water solubility and interface interactions. DPPC-PE is pivotal in studying membrane dynamics, offering insights into phase behavior, permeability, and mechanical stability under various conditions. It enables researchers to investigate the effects of lipid composition on cellular processes like vesicle formation, membrane-protein interactions, and the structural organization within lipid rafts, thereby advancing our understanding of membrane-associated signaling and transport mechanisms. This research is crucial for elucidating fundamental cellular mechanisms and contributing to advancements in nanotechnology and materials science, strictly within non-medical or pharmaceutical frameworks.