The term RAET1L refers to a gene or protein that may be related to the RAET1 (Retinoic Acid Early Transcript 1) family, which is a group of proteins that can be involved in cellular signaling processes. RAET1L Activators would include molecules designed to modulate the function of the RAET1L protein. These activators would be engineered to increase the functional activity of RAET1L, either by enhancing its expression, promoting its stability, facilitating its interaction with other signaling molecules, or by directly stimulating its activity in signal transduction pathways. The discovery of such activators would typically involve a deep understanding of the biological role of RAET1L, the pathways it participates in, and the structural features that are key to its function.
To identify RAET1L Activators, researchers would first develop an assay system to measure the activity of RAET1L. These assays could be based on the detection of downstream signaling events triggered by RAET1L activation, changes in gene expression profiles, or direct measurement of biochemical activity if the RAET1L protein has enzymatic functions. With an effective assay in place, large libraries of small molecules could be screened to identify compounds that enhance RAET1L activity. Such screening campaigns would yield initial 'hit' molecules that, after being identified, would require further validation to confirm their specificity and direct effect on RAET1L. These secondary assays might include various controls with related proteins to ensure the specificity of the activator for RAET1L, as well as dose-response and kinetic studies to characterize the interaction dynamics. Subsequent research would likely delve into the molecular mechanism by which these activators enhance RAET1L function. Approaches such as mutational analysis of the RAET1L protein, or biophysical methods like nuclear magnetic resonance (NMR) spectroscopy, could provide insights into how the activators bind and stimulate RAET1L. Understanding the interaction between RAET1L and its activators could provide valuable information about the protein's role in cellular processes.
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Nome del prodotto | CAS # | Codice del prodotto | Quantità | Prezzo | CITAZIONI | Valutazione |
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5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Come inibitore della DNA metiltransferasi, potrebbe demetilare i promotori genici e aumentare l'espressione di geni come RAET1L. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Inibendo le istone deacetilasi, il sodio butirrato può influenzare la struttura della cromatina e l'espressione dei geni, tra cui potenzialmente RAET1L. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Noto per regolare l'espressione genica, anche l'acido retinoico potrebbe influenzare l'espressione di RAET1L, data la somiglianza nella nomenclatura. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
È un agonista PPAR-gamma che può modulare l'infiammazione, influenzando potenzialmente l'espressione di proteine correlate al sistema immunitario come RAET1L. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Grazie alle sue proprietà antinfiammatorie e antiossidanti, la curcumina potrebbe modulare l'espressione dei geni correlati al sistema immunitario, tra cui RAET1L. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Questo composto ha vari effetti biologici, tra cui la modulazione della funzione immunitaria, che potrebbe potenzialmente influenzare l'espressione di RAET1L. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
Utilizzato nel trattamento di alcune leucemie, il triossido di arsenico può indurre risposte di stress nelle cellule, influenzando probabilmente l'espressione di RAET1L. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
La principale catechina del tè verde, l'EGCG, ha dimostrato di modulare le risposte immunitarie e potrebbe influenzare l'espressione di RAET1L. |