Date published: 2026-4-23

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CD229 Activators

The CD229 Activators represent a distinctive class of molecules primarily involved in modulating cellular signaling cascades and immune responses. CD229, also known as Ly9, is a surface glycoprotein expressed on various immune cells, including B and T lymphocytes. This transmembrane receptor plays a crucial role in immune regulation and cell adhesion. The CD229 Activators are characterized by their ability to interact specifically with the extracellular domain of CD229, triggering a series of intracellular events.

At the molecular level, CD229 Activators are often small organic compounds or peptides that possess a high affinity for the binding site on the CD229 receptor. Upon binding, these activators induce conformational changes in the CD229 protein, leading to the initiation of downstream signaling pathways. The activation of CD229 is intricately linked to the modulation of immune cell activities, including cell adhesion, proliferation, and cytokine production. Researchers have been keenly exploring the potential of CD229 Activators as tools to decipher the intricate regulatory networks governing immune responses. Understanding the nuanced interplay between CD229 and its activators can shed light on the fundamental mechanisms governing immune cell behavior, paving the way for insights into the broader landscape of immune system modulation. Ongoing investigations into the specific structural and functional attributes of CD229 Activators contribute to the growing understanding of immune cell regulation, holding promise for advancements in various fields related to immunology and cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA is a potent activator of protein kinase C (PKC), a key regulator of immune signaling. PKC activation can lead to increased expression and/or activity of many immune receptors, potentially including CD229.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Ionomycin is a calcium ionophore that raises intracellular calcium levels, stimulating various cellular processes including immune cell activation. It might indirectly enhance CD229 signaling by promoting overall immune activation.