Trypsin Inhibitor, soybean CAS: 9035-81-8

Trypsin Inhibitor, soybean (CAS 9035-81-8)

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Noms alternatifs: Trypsin Inhibitor, soybean is also known as SBTI.
Application: Trypsin Inhibitor, soybean is a protein and inhibitor of trypsin factor Xa, plasmin and neutrophil elastase.
Numéro CAS: 9035-81-8
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
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Trypsin Inhibitor, soybean (STI) is a protein which reduces trypsin (a proteolytic enzyme) as well as plasma kallikrein and plasmin. activity. Trypsin Inhibitor, soybean has demonstrated inhibition of human neutrophil elastase at an IC50=0.3nM. At this concentration Trypsin Inhibitor, soybean showed neither cytotoxic nor haemolytic effects on populations of human blood cells. In fibrin matrix, and without toxic effects, Trypsin Inhibitor, soybean had strong inhibitory effect on human umbilical vein endothelial cells migration and tubulogenesis. It has been observed that repeated administration of Trypsin Inhibitor, soybean to rats, especially suckling and young rats, causes the pancreas to enlarge. Trypsin Inhibitor, soybean is also known as SBTI, STI, and Trypsin inhibitor from Glycine max.


Références

1. Wilson, P.A., et al. 1978. Gut. 19: 260-266. PMID: 348580

2. Shakiba, Y., et al. 2007. Fitoterapia. 78: 587-589. PMID: 17590534

3. Ribeiro, J.K., et al. 2010. Eur J Pharmacol. PMID: 20624384

Apparence :
Powder
État Physique :
Solid
Dérivé de :
Soy Bean
Solubilité :
Soluble in water (10 mg/ml), phosphate buffers (10 mg/ml), and balanced salt solutions (1 mg/ml).
STOCKAGE :
Store at 4° C
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
WGK Allemagne :
3
Numéro MDL :
MFCD00082103
Numéro CE :
232-906-9

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Trypsin Inhibitor, soybean (CAS 9035-81-8)  Références bibliographiques

Consultez les publications faisant référence à l' utilisation de Trypsin Inhibitor, soybean (CAS 9035-81-8). Cliquez sur le lien pour afficher lentrée PubMed .

Citations 1 à 10 sur un total de 13

PMID: # 33407092  Bautista-Amorocho, H.|Silva-Sayago, JA.|Goyeneche-Patino, DA.|Pérez-Cala, TL.|Macías-Gómez, F.|Arango-Viana, JC.|Martínez, A.| et al. 2021. BMC Mol Cell Biol. 22: 1.

PMID: # 18466892  Psenicka, M. et al. 2008. Cryobiology. 56: 251-253.

PMID: # 17640870  Conners, R. et al. 2007. J. Biol. Chem. 282: 27760-27768.

PMID: # 17171473  Oshima, K. et al. 2007. J. Assoc. Res. Otolaryngol. 8: 18-31.

PMID: # 16319066  Harikumar, KG. et al. 2006. J. Biol. Chem. 281: 2543-2550.

PMID: # 16982799  Csordás, G. et al. 2006. J. Cell Biol. 174: 915-921.

PMID: # 15644453  Taylor, EB. et al. 2005. Am. J. Physiol. Endocrinol. Metab. 288: E1055-E1061.

PMID: # 16228192  Wang, KJ. et al. 2005. Theor. Appl. Genet. 112: 66-71.

PMID: # 15382080  Kobayashi, H. et al. 2004. Int. J. Cancer. 112: 519-524.

PMID: # 15168733  Kobayashi, H. et al. 2004. Clin. Exp. Metastasis. 21: 159-166.

Citations 1 à 10 sur un total de 13
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