Anti-L'anticorps TBL1 H-3 est un monoclonal IgG1 κ L'Anticorps TBL1, cité dans 3 publications, fourni en 200 µg/ml
dirigé contre les acides aminés 211-577 de TBL1X d'origine human
L'Anticorps TBL1 (H-3) est recommandé pour la détection de TBL1X of mouse, rat and human origin and TBL1Y of human origin par WB, IP, IF et ELISA
Anti-L'Anticorps TBL1 (H-3) est disponible conjugué à l'agarose pour IP; à l'HRP pour WB, IHC(P) et ELISA; et soit à la phycoerythrin ou FITC pour IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 ou Alexa Fluor® 647 pour WB (RGB), IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 680 ou Alexa Fluor® 790 pour WB (NIR), IF et FCM
Réactifs TransCruz pour une application en ChIP (sc-137006 X, 200 µg/0.1 ml)
Contactez notre Service Technique (ou votre Distributeur local) pour plus d'informations pour recevoir un échantillon GRATUIT de 10 µg de TBL1 (H-3): sc-137006.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred secondary detection reagent for TBL1 Antibody (H-3) for WB applications. This reagent is now offered in a bundle with TBL1 Antibody (H-3) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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TBL1 Antibody (H-3) is a high quality monoclonal TBL1 antibody (also designated TBL1 antibody) suitable for the detection of the TBL1 protein of mouse, rat and human origin. TBL1 Antibody (H-3) is available as both the non-conjugated anti-TBL1 antibody form, as well as multiple conjugated forms of anti-TBL1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. TBL1, for transducin β-like 1, is a ubiquitously expressed protein that contains six distinct β-transducin repeats, known also as WD40 repeats, within the C-terminal domain. Transducin β-like 1 Y-linked protein (TBL1Y), also designated F-box-like/WD-repeat protein, and transducin β-like 1 X protein (TBL1X), also known as SMAP55, are nuclear F-box-like proteins. They are important in the ubiquitin/19S proteasome complex recruitment to nuclear receptor-regulated transcription units. TBL1X is a part of the N-CoR repressor complex together with N-CoR1, N-CoR2, HDAC3, TBL1R, CORO2A and GPS2. It is also a component of the E3 ubiquitin ligase complex. TBL1X, which can interact with Histones H2B, H3a and H4, is similar to TBL1Y but is localized on chromosome Xp22.3. Defects in TBL1X may cause an X-linked human disorder called ocular albinism with late-onset sensorineural deafness (OASD). TBL1Y is an X-degenerate gene that is homologous to TBL1X. TBL1Y, a single-copy gene, localizes to human chromosome Yp11.2 in the male-specific region of chromosome Y (MSY). This region of the Y chromosome does not engage in X-Y crossover events. TBL1Y is primarily expressed in fetal brain and prostate. TBL1X and TBL1Y are crucial in nuclear receptor mediated transcription activation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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