Sinomenine hydrochloride CAS: 6080-33-7
MF: C19H23NO4•HCl
MW: 365.85
A natural anti-inflammatory morphinan analog.

Sinomenine hydrochloride (CAS 6080-33-7)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 138ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Noms alternatifs: 9α,13α,14α -7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one hydrochloride
Application: Sinomenine hydrochloride is a natural anti-inflammatory morphinan analog
Numéro CAS: 6080-33-7
Pureté: ≥98%
Masse Moléculaire: 365.85
Formule Moléculaire: C19H23NO4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
loading

Sinomenine hydrochloride is a natural anti-inflammatory morphinan analog. Sinomenine hydrochloride causes degranulation of mast cells in mammalian tissues to release histamine and suppresses production of proinflammatory cytokines. Sinomenine hydrochloride also displays antinociceptive activity, possibly through activation of the μ-opioid receptor. Stimulates short-term renewal of human embryonic stem cells (ESCs) in vitro.


Références

1. Yamasaki, H., et al., 1976. Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. Acta medica Okayama. 30(1): 1-20. PMID: 61710
2. Desbordes, Sabrina C., et al., 2008. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell stem cell. 2(6): 602-12. PMID: 18522853
3. Wang, Mao Hsien., et al., 2008. Activation of opioid mu-receptor by sinomenine in cell and mice. Neuroscience letters. 443(3): 209-12. PMID: 18692550

État Physique :
Solid
Solubilité :
Soluble in water (20 mg/ml), ethanol (~5 mg/ml), DMSO (~30 mg/ml), DMF (~30 mg/ml), and methanol.
STOCKAGE :
Store at 4° C
Point de fusion :
235-237° C
Indice de Réfraction :
n20D ~1.62 (Predicted)
Activité Optique :
α20D -80°±10°, c = 1 in water; α20D -91.6°, c = 1.05 in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
QD2163000
PubChem CID :
Numéro MDL :
MFCD01714307
SMILES :
CN1CC[[email protected]@]23CC(=O)C(=C[[email protected]@H]2[[email protected]@H]1CC4=C3C(=C(C=C4)OC)O)OC.Cl

Télécharger la Fiche de Sécurité/ SDS (MSDS)

CERTIFICAT D'ANALYSE

Pour une bonne lecture, Adobe Acrobat Reader est requis,
imprimer et commenter les documents PDF

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 107ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;