PluriSln 1 CAS: 91396-88-2
MF: C12H11N3O
MW: 213.24
PluriSln 1 is a SCD1 inhibitor and apoptosis inducer.

PluriSln 1 (CAS 91396-88-2)

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Noms alternatifs: 4-Pyridinecarboxylic acid 2-phenylhydrazide
Application: PluriSln 1 is a SCD1 inhibitor and apoptosis inducer
Numéro CAS: 91396-88-2
Masse Moléculaire: 213.24
Formule Moléculaire: C12H11N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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PluriSln 1 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1). It is useful for eliminating undifferentiated human pluripotent stem cells (hPSCs) from culture by selectively inducing apoptosis in these cells. Additionally, pluriSln 1 induces endoplasmic reticulum stress, reduces protein synthesis, and prevents teratoma formation in immunocompromised mice models.


Références

1. Ben-David, Uri., et al., 2013. Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell stem cell. 12(2): 167-79. PMID: 23318055

État Physique :
Solid
STOCKAGE :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1=CC=C(C=C1)NNC(=O)C2=CC=NC=C2

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CERTIFICAT D'ANALYSE

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