Anticorps NDUFA10 (F-4): sc-376046

NDUFA10 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10), also known as CI-42KD, is a 355 amino acid protein that localizes to the mitochondrial matrix and functions as an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase complex I. Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration. NDUFA10 uses FAD as a cofactor and works in conjunction with other proteins to mediate complex I function and to ensure the proper transfer of electrons within the respiratory chain. The gene encoding NDUFA10 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin ichthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

L'anticorps NDUFA10 préféré est l'Anticorps NDUFA10 (A-8): sc-376357.