ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
LASP-1 (LIM and SH3 domain protein 1), also known as MLN50, is a 261 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one SH3 domain, one LIM zinc-binding domain and two nebulin repeats. Expressed as two alternatively spliced isoforms, LASP-1 interacts with F-Actin and plays an important role in the regulation of Actin-associated cytoskeletal organization. LASP-1 is subject to post-translational phosphorylation, an event which may regulate Actin-related ion transport activities in epithelial cells. Overexpression of LASP-1 is associated with breast cancer, suggesting a role for LASP-1 in tumor transformation and metastasis. The gene encoding LASP-1 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps LASP-1 (KK-M25) | sc-134379 | 100 µg/ml | $333.00 |