Anticorps CLEC-1 (E-1): sc-390005
- L'Anticorps CLEC-1 (E-1) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 124-224 dans une région interne de CLEC-1 d'origine human
- recommandé pour la détection de CLEC-1 d'origine human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour CLEC-1 Antibody (E-1) for WB applications. Ces réactifs sont désormais proposés en lots avec CLEC-1 Antibody (E-1)(voir les informations de commande ci-dessous).
The human β-glucan protein (Dectin-1) is a small, type II transmembrane receptor that enables β-glucan-dependent, nonopsonic recognition of zymosan and other yeast-derived particles by primary macrophages. Dectin-1 is the human homolog of the C-type (calcium dependent) lectin-like receptor (CLEC) family that play an important role in regulating innate immunity. CLEC-1 is a 280 amino acid single-pass type II transmembrane protein expressed in dendritic and endothelial cells. It accumulates in perinuclear compartments and requires an associated chain to reach the cell surface. CLEC-1 is involved in antigen uptake and is homologous to the natural killer (NK) cell receptors, NKG2s and CD94, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. It has a single carbohydrate recognition domain with six conserved and two additional cysteine residues. Additionally, CLEC-1 has a cytoplasmic immuno-receptor tyrosine-based motif and many potential phosphorylation sites.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps CLEC-1 (E-1) | sc-390005 | 200 µg/ml | $316.00 | |||
CLEC-1 (E-1): m-IgG Fc BP-HRP Kit | sc-540738 | 200 µg Ab; 10 µg BP | $354.00 | |||
CLEC-1 (E-1): m-IgG1 BP-HRP Kit | sc-542337 | 200 µg Ab; 20 µg BP | $354.00 |