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Mahogany (MG), originally identified as a protein involved in pigmentation, acts in conjunction with melanocortin receptors to suppress diet-induced obesity. Mahogany contains a single transmembrane domain, and it is expressed in a broad range of tissues, including the hypothalamus and pigment cells. Mutations within the mahogany gene were shown to rescue agouti-lethal-yellow mutant mice from obesity. The extracellular domain of mouse mahogany is the ortholog of the human protein attractin. Attractin (also designated DPPT-L) is a human serum glycoprotein and is a member of the CUB family of cell adhesion and guidance proteins. Attractin is expressed on activated T cells and is released from the cells 48 to 72 hours after activation.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Attractin (F-2) | sc-514036 | 200 µg/ml | $316.00 | |||
Attractin (F-2): m-IgG Fc BP-HRP Kit | sc-538573 | 200 µg Ab; 10 µg BP | $354.00 | |||
Attractin (F-2): m-IgGκ BP-HRP Kit | sc-536211 | 200 µg Ab; 40 µg BP | $354.00 | |||
Attractin (F-2): m-IgG1 BP-HRP Kit | sc-545774 | 200 µg Ab; 20 µg BP | $354.00 |