L'Anticorps Annexin VI (C-4) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
spécifique d'un épitope situé entre les acides aminés 119-149 près de N-terminus de Annexin VI d'origine human
recommandé pour la détection de Annexin VI d'origine mouse, rat et human par WB, IP, IF et ELISA
m-IgG Fc BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps Annexin VI (C-4) pour des applications de WB. Ces réactifs sont maintenant proposés en kit avec l'anticorps Annexin VI (C-4) (voir Informations pour la commande ci-dessous).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
ACCÈS RAPIDE AUX LIENS
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca++-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A-431 cells, Annexin VI causes a partial reversal of the transformed phenotype. It has been hypothesized that growth-dependent posttranslational modifications of Annexins are required for proper sub-cellular localization. Annexin VII, also referred to as synexin, is located at the plasma membrane in nor-mal muscle tissue. However, in muscle samples from patients suffering from Duchenne′s muscular dystrophy, Annexin VII, along with Annexins IV and VI, is released into the cytoplasm and later, as the disease progresses, into the extracellular space. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.