Anti-WSB1 Anticuerpo A-10 es un monoclonal de ratón IgG1 (kappa light chain) WSB1 Anticuerpo proporcionado como 200 µg/ml
específico para un epítopo localizado entre los amino ácidos 387-408 cerca del C-terminus de WSB1 oe orgiendf humanorigin
WSB1 Anticuerpo (A-10) es recomendado para detectar WSB1 de mouse, rat y human origen, mediante WB, IP, IF y ELISA; también reactivo con otras especies, incluyendo anyd equine, canine, bovine and porcine
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for WSB1 Antibody (A-10) for WB applications. These reagents are now offered in bundles with WSB1 Antibody (A-10) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
WSB1 Antibody (A-10) is a high quality monoclonal WSB1 antibody (also designated WSB1 antibody) suitable for the detection of the WSB1 protein of mouse, rat and human origin. WSB1 Antibody (A-10) is available as both the non-conjugated anti-WSB1 antibody form, as well as multiple conjugated forms of anti-WSB1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.