TMEM205 Anticuerpo (G-1) es un monoclonal de ratón IgG2b (kappa light chain) proporcionado como 200 µg/ml
específico para un epítopo localizado entre los amino ácidos 129-144 de la región interna de TMEM205 de origen human
recomendado para detectarTMEM205 de mouse, rat y human origen, mediante WB, IP, IF y ELISA; también reactivo con otras especies, incluyendo canine
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TMEM205 Antibody (G-1) for WB applications. These reagents are now offered in bundles with TMEM205 Antibody (G-1) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts that activate signaling pathways culminating in apoptosis. Cisplatin has been suggested to induce apoptosis through caspase-3 activation and XIAP expression. TMEM205 is a 189 amino acid transmembrane protein that is expressed in liver, pancreas, and adrenal glands. Elevated levels of Rab 8 and TMEM205 in cells may be associated with cisplatin resistance. TMEM205 is suggested to be a biomarker or target in cancer chemotherapy. TMEM205 is encoded by a gene located on human chromosome 19, which consist of around 63 million bases with over 1,400 genes, and makes up over 2% of human genomic DNA.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.