Phosphatase Inhibitor Cocktail C Inhibidor de fosfatasas alcalinas y Ser/Thr utilizado para la investigación

Phosphatase Inhibitor Cocktail C

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Nombres Alternativos: Phosphatase Inhibitor Cocktail C is also known as Phosphatase Inhibitor Cocktail Set IV.
Solicitud: Phosphatase Inhibitor Cocktail C is an inhibitor of alkaline and ser/thr phosphatases used for research purposes
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
* En el Certificado de Análisis específico de lote, puede encontrar información específica (como el contenido en agua).
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Phosphatase Inhibitor Cocktail C acts as an inhibitor of alkaline, and serine/threonine phosphatases. The compound is composed of the following inhibitors: Cantharidin (sc-201321), (−)-p-Bromotetramisole oxalate (sc-201431), and Calyculin A (sc-24000). Cantharidin and Calyculin A are effective PP-1/PP2A phosphatase inhibitors and (−)-p-Bromotetramisole oxalate acts as a protein-tyrosine phosphatase inhibitor. Alkaline phosphatases are part of a group called phosphomonoesterases, which hydrolyze phosphate esters. Serine/threonine phosphatases are reported to be located in the cytoplasm and play an important role in signal transduction and transcriptional activation.


References

1. Vroon, D.H. et al. 1990. Clin. Meth. PMID: 21250047

2. Kitamura, T. et al. 2000. Brain Res. 854(1-2): 165-171. PMID: 10784118

3. Ivanova, T.I. et al. 2006. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 145(1): 60-67. PMID: 16875859

4. Kitazawa, T. 2010. Biochem. Biophys. Res. Commun. 401(1): 75-78. PMID: 20833141

5. Campbell, B.E. et al. 2011. Biotechnol. Adv. 29(1): 28-39. PMID: 20732402

Uso :
Following initial thaw, aliquot and freeze (-20° C). Dilute 1:50 just prior to use.
Estado de Materia :
Liquid
ALMACENAMIENTO :
Store at -20° C
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.

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CERTIFICADO DE ANÁLISIS

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Phosphatase Inhibitor Cocktail C  Menciones del Producto

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Citaciones 1 a 10 de un total de 28

PMID: # 31112400  Patten, DA.|Ouellet, M.|Allan, DS.|Germain, M.|Baird, SD.|Harper, ME.|Richardson, RB.| et al. 2019. FASEB J. 33: 9263-9278.

PMID: # 31167138  Gil-Ranedo, J.|Gonzaga, E.|Jaworek, KJ.|Berger, C.|Bossing, T.|Barros, CS.| et al. 2019. Cell Rep. 27: 2921-2933.e5.

PMID: # 31135337  Bigot, N.|Day, M.|Baldock, RA.|Watts, FZ.|Oliver, AW.|Pearl, LH.| et al. 2019. Elife. 8:

PMID: # 31488816  2019. Nat Commun. 10: 3991.

PMID: # 30142917  Hernandez-Valencia, J. et al. 2018. Nutrients. 10:

PMID: # 28460481  Kang, HJ. et al. 2017. Oncotarget. 8: 27263-27276.

PMID: # 26723877  Seol, HS. et al. 2016. Cancer Lett. 372: 24-35.

PMID: # 27141997  Fortunato, TM. et al. 2016. Scientific reports. 6: 25326.

PMID: # 27596264  Kim, M. et al. 2016. Sci Rep. 6: 32770.

PMID: # 25496996  Rabizadeh, E. et al. 2015. Thromb. Res. 136: 118-24.

Citaciones 1 a 10 de un total de 28
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