PGRP-L Anticuerpo (A-5) es un monoclonal de ratón IgG2a (kappa light chain) proporcionado como 200 µg/ml
producido contra los amino ácidos 23-322 localizados cerca del N-terminus de PGRP-L de origen mouse
recomendado para detectar PGRP-L de mouse origen, mediante WB, IP, IF, IHC(P) y ELISA
m-IgG2a BP-HRP is the preferred secondary detection reagent for PGRP-L Antibody (A-5) for WB and IHC(P) applications. This reagent is now offered in a bundle with PGRP-L Antibody (A-5) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Peptidoglycan recognition protein-L (PGRP-L) is a pattern recognition molecule consisting of 576 amino acid residues. It is the longest and most widely expressed member of the PGRP family. PGRP-L is a Zn2+-dependent protein with N-acetylmuramyl-L-alanine-amidase activity that digests peptidoglycan. PGRP-L can form a homodimer and may dimerize with other PGRP proteins. It is a secreted serum protein but is also expressed as a transmembrane protein in liver parenchymal cells binding peptidoglycan and Gram-positive bacteria. PGRP-L deficient mice exhibit slightly lower levels of IL-6 and TNFα but exhibit no obvious phenotypic abnormalities. This suggests that PGRP-L may play a minor role in innate immune functions. In addition, PGRP-L may be a key player in the activation of Nod1, an intracellular pattern recognition protein.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.