Ninjurin-1 Antibody (50): sc-136295
- Ninjurin-1 Antibody (50) is a mouse monoclonal IgG2a κ Ninjurin-1 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 1-152 representing full length Ninjurin-1 of human origin
- recommended for detection of Ninjurin-1 of mouse, rat, human and canine origin by WB and IF; not recommended for IP
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ninjurin-1 Antibody (50) for WB applications. These reagents are now offered in bundles with Ninjurin-1 Antibody (50) (see ordering information below).
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Ninjurin-1 Antibody (50) is a mouse monoclonal IgG2a kappa light chain antibody that detects Ninjurin-1 protein of mouse, rat, human, and canine origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-Ninjurin-1 antibody (50) is available as the non-conjugated format. Ninjurin-1 is a crucial member of the Ninjurin family, which consists of multi-pass membrane proteins that are notably induced by nerve injury in Schwann cells and dorsal root ganglion neurons. These proteins function as homophilic cell adhesion molecules, facilitating axonal growth and contributing to repair processes following nerve damage. Ninjurin-1 extends beyond neuronal contexts, playing a vital role in the formation and function of various epithelial tissues, highlighting Ninjurin-1′s role in both development and tissue homeostasis. Ninjurin-1 is widely expressed across adult and embryonic tissues, particularly in those of epithelial origin, underscoring Ninjurin-1′s significance in cellular interactions and signaling pathways.
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Ninjurin-1 Antibody (50) References:
- Ninjurin2, a novel homophilic adhesion molecule, is expressed in mature sensory and enteric neurons and promotes neurite outgrowth. | Araki, T. and Milbrandt, J. 2000. J Neurosci. 20: 187-95. PMID: 10627596
- Ninjurin1 increases p21 expression and induces cellular senescence in human hepatoma cells. | Toyama, T., et al. 2004. J Hepatol. 41: 637-43. PMID: 15464245
- Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage. | Cardoso, CC., et al. 2007. J Neuroimmunol. 190: 131-8. PMID: 17825431
- DNA polymorphisms as tools for spinal cord injury research. | Guimarães, PE., et al. 2009. Spinal Cord. 47: 171-5. PMID: 18504448
- Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth. | Araki, T. and Milbrandt, J. 1996. Neuron. 17: 353-61. PMID: 8780658
- Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule. | Araki, T., et al. 1997. J Biol Chem. 272: 21373-80. PMID: 9261151
- The human homologue of the ninjurin gene maps to the candidate region of hereditary sensory neuropathy type I (HSNI). | Chadwick, BP., et al. 1998. Genomics. 47: 58-63. PMID: 9465296
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ninjurin-1 Antibody (50) | sc-136295 | 200 µg/ml | $322.00 | |||
Ninjurin-1 Antibody (50): m-IgG Fc BP-HRP Bundle | sc-528810 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ninjurin-1 Antibody (50): m-IgGκ BP-HRP Bundle | sc-521354 | 200 µg Ab, 40 µg BP | $361.00 | |||
Ninjurin-1 Antibody (50): m-IgG2a BP-HRP Bundle | sc-547177 | 200 µg Ab; 10 µg BP | $361.00 |