Anti-NASP Anticuerpo A-7 es un monoclonal de ratón IgG2a κ NASP Anticuerpo, ver las 2 publicaciones, proporcionado como 200 µg/ml
específico para un epítopo localizado entre los amino ácidos 550-572 de la región interna de NASP de origen human
NASP Anticuerpo (A-7) es recomendado para detectar NASP de mouse, rat y human origen, mediante WB, IP, IF, IHC(P) y ELISA
NASP Anticuerpo (A-7) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de NASP (A-7): sc-514669.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for NASP Antibody (A-7) for WB and IHC(P) applications. These reagents are now offered in bundles with NASP Antibody (A-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
NASP Antibody (A-7) is a high quality monoclonal NASP antibody (also designated NASP antibody) suitable for the detection of the NASP protein of mouse, rat and human origin. NASP Antibody (A-7) is available as both the non-conjugated anti-NASP antibody form, as well as multiple conjugated forms of anti-NASP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Histones, the chief components of chromatin, are required for the formation of core nucleosomes around which DNA can wind and they play an essential role in DNA condensation and gene regulation. The transport of histones to the nucleus is crucial to ensuring proper nucleosome assembly and, ultimately, DNA replication. NASP (nuclear autoantigenic sperm protein) is a 788 amino acid protein that localizes to both the nucleus and the cytoplasm and contains three TPR repeats. Expressed as multiple alternatively-spliced isoforms, one of which is testis- and sperm-specific (tNASP) and the other expressed in somatic cells (sNASP), NASP functions as a Histone H1 binding protein that mediates histone transport to the nucleus and is required for normal cell cycle progression and cellular proliferation. Due to its testicular expression and important role in DNA replication and cell cycle events, NASP is necessary for spermatogenesis and normal development. Upon DNA damage, NASP may be phosphorylated by ATM or ATR.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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