Anti-Myosin XVIIIB Anticuerpo D-11 es un monoclonal de ratón IgG1 κ Myosin XVIIIB Anticuerpo, ver las 1 publicaciones, proporcionado como 200 µg/ml
producido contra los amino ácidos 1801-1930 localizados en la región interna de Myosin XVIIIB de origen human
Myosin XVIIIB Anticuerpo (D-11) es recomendado para detectar Myosin XVIIIB isoforms 1 and 2 de mouse, rat y human origen, mediante WB, IP, IF y ELISA
Myosin XVIIIB Anticuerpo (D-11) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de Myosin XVIIIB (D-11): sc-515011.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for Myosin XVIIIB Antibody (D-11) for WB applications. These reagents are now offered in bundles with Myosin XVIIIB Antibody (D-11) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Myosin XVIIIB Antibody (D-11) is a high quality monoclonal Myosin XVIIIB antibody (also designated Myosin XVIIIB antibody) suitable for the detection of the Myosin XVIIIB protein of mouse, rat and human origin. Myosin XVIIIB Antibody (D-11) is available as both the non-conjugated anti-Myosin XVIIIB antibody form, as well as multiple conjugated forms of anti-Myosin XVIIIB antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Myosin XVIIIB (MYO18B) is a 2,567 amino acid, unconventional myosin heavy chain that is expressed mainly in human cardiac and skeletal muscles and, at much lower levels, in the testis. Myosin XVIIIB is located in the cytoplasm of undifferentiated myoblast cells and has an N-terminal head domain functioning as a motor (with an ATP-binding site as well as an actin-binding region), a neck region containing an IQ motif, and a C-terminal tail with a short coiled-coil domain allowing for dimerization to form a 2-headed structure. Sug1, a regulator of the 26S proteasome, binds to the C-terminal tail of Myosin XVIIIB. This Sug1 binding causes an upregulation of Myosin XVIIIB. Myosin XVIIIB is frequently deleted, mutated and/or hypermethylated in lung and ovarian cancers, suggesting its candidacy as a tumor-suppressor. Furthermore, the Histones H3 and H4 play a role in the regulation of Myosin XVIIIB expression, so histone deacetylation surrounding the promoter region may be involved in lung and ovarian carcinomas.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences