Anti-MTA1 Anticuerpo E-12 es un monoclonal de ratón IgG2a κ MTA1 Anticuerpo, ver las 7 publicaciones, proporcionado como 200 µg/ml
específico para un epítopo localizado entre los amino ácidos 669-703 cerca del C-terminus de MTA1 oe orgiendf humanorigin
MTA1 Anticuerpo (E-12) es recomendado para detectar MTA1 de mouse, rat y human origen, mediante WB, IP, IF, IHC(P) y ELISA
MTA1 Anticuerpo (E-12) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de MTA1 (E-12): sc-373765.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for MTA1 Antibody (E-12) for WB and IHC(P) applications. These reagents are now offered in bundles with MTA1 Antibody (E-12) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MTA1 Antibody (E-12) is a high quality monoclonal MTA1 antibody (also designated MTA1 antibody) suitable for the detection of the MTA1 protein of mouse, rat and human origin. MTA1 Antibody (E-12) is available as both the non-conjugated anti-MTA1 antibody form, as well as multiple conjugated forms of anti-MTA1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. MTA1 (metastasis-associated protein 1) is a component of the NURD (nucleosome remodeling and histone deacetylation) complex, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity. MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin. Structurally, MTA1 contains a single SH3-binding motif and a zinc finger domain, along with a region similar to the co-repressor protein N-Cor. MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis. Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, gastrointestinal and breast carcinomas. Elevation of MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, increase mammary cell motility and potentiate growth, and therefore may be an indicator for assessing the potential malignancies of various tumors. A similar protein, MTA2, also designated MTA1-L1 (MTA1-like protein 1), shares more than 55% sequence homology with MTA1 and is ubiquitously expressed.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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