MYL9/MYL12A/B Anticuerpo (D-9)recomendado para detectar the myosin regulatory light chains encoded by MYL9, MYL12A and MYL12B, and the LOC391722 protein of human origin; Mylc2b, Myl9 and Myl12a of mouse origin; and Mrlcb and Myl9 of rat origin medainte WB, IP, IF, IHC(P) y ELISA
MYL9/MYL12A/B Anticuerpo (D-9) es un monoclonal de ratón IgG1 κ, ver las 8 publicaciones, proporcionado como 200 µg/ml
raised against amino acids 1-172 representing full length MRCL3 of human origin
recomendado para detectar the myosin regulatory light chains encoded by MYL9, MYL12A and MYL12B, and the LOC391722 protein of human origin; Mylc2b, Myl9 and Myl12a of mouse origin; and Mrlcb and Myl9 of rat origin medainte WB, IP, IF, IHC(P) y ELISA
Ver MYL9/MYL12A/B (E-4): sc-28329 para MYL9/MYL12A/B anticuerpos conjugados, incluyendo AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 y 790.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for MYL9/MYL12A/B Antibody (D-9) for WB and IHC(P) applications. These reagents are now offered in bundles with MYL9/MYL12A/B Antibody (D-9) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of myosin have been cloned: smooth muscle myosins, striated muscle myosins and non-muscle myosins. Myosin regulatory light chains, including MYL12A (also known as MRLC3 or MLCB), MYL12B (also known as MRLC2) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.