MYL12A/B Anticuerpo (A-10)recomendado para detectar the myosin regulatory light chains encoded by MYL12A and MYL12B of human origin, Mylc2b of mouse origin and Mrlcb of rat origin medainte WB, IP, IF, IHC(P) y ELISA
MYL12A/B Anticuerpo (A-10) es un monoclonal de ratón IgG2b κ, ver las 3 publicaciones, proporcionado como 200 µg/ml
específico para un epítopo localizado entre los amino ácidos 103-141 de la región interna de MRCL3 de origen human
MYL12A/B Anticuerpo (A-10) es recomendado para detectar the myosin regulatory light chains encoded by MYL12A and MYL12B of human origin, Mylc2b of mouse origin and Mrlcb of rat origin medainte WB, IP, IF, IHC(P) y ELISA; también reactivo con otras especies, incluyendo anyd equine, canine, bovine and porcine
MYL12A/B Anticuerpo (A-10) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de MYL12A/B (A-10): sc-376606.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) is the preferred secondary detection reagent for MYL12A/B Antibody (A-10) for WB and IHC(P) applications. This reagent is now offered in a bundle with MYL12A/B Antibody (A-10) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of myosin have been cloned: smooth muscle myosins, striated muscle myosins and non-muscle myosins. Myosin regulatory light chains, including MYL12A (also known as MRLC3 or MLCB), MYL12B (also known as MRLC2) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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