Integrin β2/ITGB2/CD18 Antibody (YTS 213.1): sc-59751

Integrin β2 Antibody (YTS 213.1) is a rat monoclonal IgG2a antibody that detects Integrin β2 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Integrin β2 plays a crucial role in cell adhesion and signaling, functioning as a key component of the integrin family of receptors that mediate interactions between cells and the extracellular matrix. Integrin β2 is primarily located on the cell surface, where Integrin β2 forms heterodimers with various α subunits, allowing binding to ligands such as Fibronectin and Collagen. Proper localization of Integrin β2 is essential for function, as Integrin β2 facilitates the transmission of signals from the extracellular environment to the cell interior, influencing processes such as cell migration, proliferation, and survival. Additionally, interaction of Integrin β2 with ligands is vital for the activation of downstream signaling pathways that regulate cellular responses to external stimuli. Anti-Integrin β2 antibody (YTS 213.1) enables researchers to gain insights into the dynamics of cell adhesion and the role of integrins in various physiological and pathological processes.

The preferred Integrin β2/ITGB2/CD18 antibody is Integrin β2/ITGB2/CD18 Antibody (CTB104): sc-8420.