Integrin β2/ITGB2/CD18 Antibody (L-13): sc-80123

Integrin β2 Antibody (L-13) is a mouse monoclonal IgG1 antibody that detects Integrin β2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Anti-Integrin β2 antibody (L-13) is raised against the extracellular domain of Integrin β2 of human origin. Integrin β2 monoclonal antibody (L-13) is a crucial component of the integrin family, which consists of heterodimers formed by noncovalently associated transmembrane α and β subunits. Anti-Integrin β2 antibody (L-13) pairs with various α subunits to form receptors that play a vital role in cell adhesion and signaling. Integrin β2 is predominantly located on the surface of leukocytes, where Integrin β2 facilitates interactions with the extracellular matrix and other cells, thereby influencing immune responses and inflammation. Proper functioning of Integrin β2 is essential for leukocyte migration and adhesion, which are critical processes in immune surveillance and response to injury. Dysregulation of Integrin β2 can lead to various pathological conditions, including autoimmune diseases and impaired wound healing. Anti-Integrin β2 antibody (L-13) is an invaluable tool for researchers studying these processes, allowing for the exploration of integrin-mediated signaling pathways and their implications in health and disease.

The preferred Integrin β2/ITGB2/CD18 antibody is Integrin β2/ITGB2/CD18 Antibody (CTB104): sc-8420.