Integrin β2/ITGB2/CD18 Antibody (1.BB.246): sc-71397
- Integrin β2/ITGB2/CD18 Antibody (1.BB.246) is a mouse monoclonal IgG1, cited in 3 publications, provided at 100 µg/ml
- raised against human leukocytes of a patient suffering from LGL-type leukemia
- recommended for detection of an epitope involving residues 534-546 in cysteine-rich repeat 3 of Integrin β2 of human origin by WB (non-reducing), IP, IF and FCM
- available conjugated to FITC for IF, IHC(P) and FCM
- also provided azide-free for biological studies, sc-71397 L, 100 µg/0.1 ml
- See Integrin β2/ITGB2/CD18 (CTB104): sc-8420 for Integrin β2/ITGB2/CD18 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Integrin β2/ITGB2/CD18 Antibody (1.BB.246). This work is in progress.
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SEE ALSO...
Integrin β2 Antibody (1.BB.246) is a mouse monoclonal IgG1 antibody that detects Integrin β2 in human samples through western blotting (WB) under non-reducing conditions, immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Integrin β2 is a crucial component of the integrin family, which consists of heterodimers formed by noncovalently associated transmembrane α and β subunits. Specifically, anti-Integrin β2 antibody (1.BB.246) recognizes proteins that pair with various α subunits to form receptors playing a vital role in cell adhesion and signaling. Integrin β2 is predominantly located on the cell surface, where Integrin β2 interacts with ligands in the extracellular matrix, such as Fibronectin and Collagen, as well as with counterreceptors on adjacent cells. This localization is essential for mediating cellular responses to the extracellular environment, influencing processes such as cell migration, proliferation, and survival. Furthermore, Integrin β2 is involved in the immune response, particularly in leukocyte adhesion and migration, making Integrin β2 a significant target for research in immunology and cancer biology. Integrin β2 monoclonal antibody (1.BB.246) serves as an invaluable tool for studying these critical biological processes and understanding the role of integrins in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin β2/ITGB2/CD18 Antibody (1.BB.246) | sc-71397 | 100 µg/ml | $322.00 | |||
Integrin β2/ITGB2/CD18 Antibody (1.BB.246) FITC | sc-71397 FITC | 100 tests in 2 ml | $336.00 | |||
Integrin β2/ITGB2/CD18 Antibody (1.BB.246) L | sc-71397 L | 100 µg/0.1 ml | $322.00 |