Integrin αE/ITGAE/CD103 Antibody (BP6): sc-53357

Integrin αE Antibody (BP6) is a mouse monoclonal IgG1 kappa light chain antibody that detects Integrin αE protein of human origin by immunoprecipitation (IP) and immunofluorescence (IF). Integrin αE, also known as ITGAE or CD103, plays a crucial role in the immune system by mediating T cell adhesion to epithelial cells, particularly in the gut, where Integrin αE is essential for intraepithelial lymphocyte retention. This localization allows for effective immune surveillance and response in mucosal tissues, contributing to intestinal homeostasis maintenance and inflammatory disease prevention. Integrin αE interaction with ligands, such as E-cadherin, facilitates stable cell-cell contact formation, critical for epithelial barrier integrity. Additionally, Integrin αE (BP6) antibody helps researchers study signaling pathways influencing T cell activation and differentiation, highlighting Integrin αE′s importance in immune regulation and tissue repair processes. Anti-Integrin αE antibody (BP6) serves as an invaluable tool for studying immune responses, epithelial biology, and related pathologies.

The preferred Integrin αE/ITGAE/CD103 antibody is Integrin αE/ITGAE/CD103 Antibody (Ber-ACT8): sc-19981.