iMAC2 inhibits mitochondrial apoptosis-induced channel (MAC) (IC50 = 28 nM). It has been shown to reduce STS-induced apoptosis in FL5.12 cells by over 50%. Inhibits release of cytochrome c by Bid-induced Bax activation (IC50 = 0.68 μM).
Estado de Materia
Soluble in DMSO (5 mM).
Store at 4° C
MAC: IC50 = 28 nM
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
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