Hexaprenylhydroquinone CAS: 119980-00-6
MF: C36H54O2
MW: 518.8
A potent inhibitor of HIV reverse transcriptase and DNA polymerase.

Hexaprenylhydroquinone (CAS 119980-00-6)

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Solicitud: Hexaprenylhydroquinone is a potent inhibitor of HIV reverse transcriptase and DNA polymerase
Número de CAS: 119980-00-6
Peso Molecular: 518.8
Fórmula Molecular: C36H54O2
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
* En el Certificado de Análisis específico de lote, puede encontrar información específica (como el contenido en agua).
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Hexaprenylhydroquinone is a potent inhibitor of HIV reverse transcriptase and cellular DNA polymerase. Inhibitor of CDC25A. Similar compounds have shown inhibitory effects on phospholipase A2.


References

1. Three new heptaprenylhydroquinone derivatives from the sponge Ircinia fasciculata: Y. Venkateswarlu and M. Venkata Rami Reddy; J. Nat. Prod. 57, 1286 (1994). 2. Biological effects of prenylated hydroquinones: structure-activity relationship studies in antimicrobial, brine shrimp, and fish lethality assays: S. De Rosa, et al.; J. Nat. Prod. 57, 1711 (1994). 3. Mode of inhibition of HIV reverse transcriptase by 2-hexaprenylhydroquinone, a novel general inhibitor of RNA-and DNA-directed DNA polymerases: S. Loya, et al.; Biochem. J. 324, 721 (1997). 4. Polyprenyl-hydroquinones and -furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A: I. Erdogan-Orhan, et al.; Nat. Prod. Res. 18, 1 (2004).

Estado de Materia :
Solid
Solubilidad :
Soluble in DMSO or 100% ethanol
ALMACENAMIENTO :
Store at -20° C
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
PubChem CID :
SMILES :
CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CC/C(=C/CC/C(=C/CC1=C(C=CC(=C1)O)O)/C)/C)/ C)/C)/C)C

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