Ets-2 Anticuerpo (E-5) es un monoclonal de ratón IgG1 κ, ver las 11 publicaciones, proporcionado como 200 µg/ml
específico para un epítopo localizado entre los amino ácidos 441-469 en el C-terminus de Ets-2 de origen human
Ets-2 Anticuerpo (E-5) es recomendado para detectar Ets-2 de mouse, rat y human origen, mediante WB, IP, IF y ELISA; también reactivo con otras especies, incluyendo anyd canine and bovine
TransCruz reactivo, para ChIP (sc-365666 X, 200 µg/0.1 ml)
Ets-2 Anticuerpo (E-5) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de Ets-2 (E-5): sc-365666.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ets-2 Antibody (E-5) for WB applications. These reagents are now offered in bundles with Ets-2 Antibody (E-5) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5′-GGAA-3′ element. Evidence indicates that the DNA binding activity by Ets-1 is regulated at the level of phosphorylation.
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