Anti-Cdc14a phosphatase Anticuerpo DCS-291 es un monoclonal de ratón IgG1 (kappa light chain) Cdc14a phosphatase Anticuerpo proporcionado como 200 µg/ml
raised against a recombinant fragment of Cdc14a phosphatase of human origin
Cdc14a phosphatase Anticuerpo (DCS-291) es recomendado para detectar Cdc14a phosphatase de human origen, mediante WB, IP y IF
Cdc14a phosphatase Anticuerpo (DCS-291) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de Cdc14a phosphatase (DCS-291): sc-56260.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Cdc14a phosphatase Antibody (DCS-291) for WB applications. These reagents are now offered in bundles with Cdc14a phosphatase Antibody (DCS-291) (see ordering information below).
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Cdc14a phosphatase Antibody (DCS-291) is a high quality monoclonal Cdc14a phosphatase antibody suitable for the detection of the Cdc14a phosphatase protein of human origin. Cdc14a phosphatase Antibody (DCS-291) is available as both the non-conjugated anti-Cdc14a phosphatase antibody form, as well as multiple conjugated forms of anti-Cdc14a phosphatase antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In budding yeast, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis. Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family. It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53. In addition, Cdc14a dephosphorylates hCdh1 and activates APCCdh1. Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, mitosis and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells. Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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