BML-282An inhibitor of ubiquitin C-terminal hydrolase L1

BML-282

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 87ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Sinónimo: N-(3,4-Dichlorobenzyl)-5-bromoisatin O-Acetyloxime
Solicitud: An inhibitor of ubiquitin C-terminal hydrolase L1
Peso Molecular: 442.08
Fórmula Molecular: C17H11BrCl2N2O3
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

BML-282 is a novel, selective inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1, IC50 = 0.81 µM) over UCH-L3 (IC50 = 17 µM).


References

1. Love, Kerry Routenberg., et al., 2007. Mechanisms, biology and inhibitors of deubiquitinating enzymes. Nature chemical biology. 3(11): 697-705. PMID: 17948018

Estado de Materia :
Solid
Solubilidad :
Soluble in DMSO (5 mg/ml) with warming, and DMF (10 mg/ml) with warming.
ALMACENAMIENTO :
Store at -20° C
IC50 :
UCH-L1: IC50 = 0.81 µM; UCH-L3 : IC50 = 17 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
C1=C2C(=CC(=C1)Br)C(C(N2CC3=CC(=C(C=C3)Cl)Cl)=O)=NOC(=O)C

Descargar SDS (MSDS)

CERTIFICADO DE ANÁLISIS

Necesita Adobe Acrobat Reader para ver de forma fiable,
imprimir y comentar el documento de PDF

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 86ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 3ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. es un líder mundial en el desarrollo de productos para el mercado de la investigación biomédica. Llámenos gratis al 00 800 4573 8000.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved."Santa Cruz Biotechnology", y el logo de Santa Cruz Biotechnology, Inc., "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", el logo de San Juan Ranch, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", y "EZ Touch" son marcas registradas de Santa Cruz Biotechnology, Inc. Todas las marcas registradas son propiedad de su respectivo dueño.