Farnesyl pyrophosphate ammonium salt, in methanol CAS: 13058-04-3
MF: C15H25O7P2•3NH4
MW: 433.42
An isoprenoid farnesyl donor.

Farnesyl pyrophosphate ammonium salt, in methanol (CAS 13058-04-3)

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Alternative Namen: FPP.3NH4; 3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt
Anwendungen Farnesyl pyrophosphate ammonium salt, in methanol is an isoprenoid farnesyl donor
CAS Nummer: 13058-04-3
Molekulargewicht: 433.42
Summenformel: C15H25O7P23NH4
Ergänzende Informationen: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Ausschließlich für Forschungszwecke. Nicht Geeignet für Verwendung in Diagnostik oder Therapie.
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Farnesyl pyrophosphate ammonium salt, in methanol, is an isoprenoid farnesyl-donor which is utilized by farnesyltransferase. It is also used for prenylation of several low molecular mass G proteins, including Ras. FPP has been shown to negate the inhibitory effects of cell growth for cells grown in high glucose conditions as well as to reverse the growth inhibitory effects of statins on variant human embryonic stem cells and cancer cells. FPP has also been detected in Alzheimer's patients brains in elevated levels. Farnesyl pyrophosphate ammonium salt is an inhibitor of P2Y12. Concentration: ~ 1 mg/ml in methanol: 10 mM ammonium hydroxide (7:3).


Literaturhinweise

1. Pompliano, D.L. 1992. Biochemistry. 31(15): 3800-3807. PMID: 1567835 2. Reiss, Y. 1992. J. Biol. Chem. 267(9): 6403-6408. PMID: 1556143 3. Gauthaman, K. 2009. Br. J. Pharmacol. 157(6): 962-973. PMID: 19438511 4. Ye, Y. 2009. FEBS Lett. 583(18): 2997-30

Formulierung :
~ 1 mg/ml in methanol: 10 mM ammonium hydroxide (7:3)
Aggregatzustand :
Liquid
LAGERUNG: :
Store at -20° C
Sidepunkt :
64° C
Ausschließlich für Forschungszwecke. Nicht Geeignet für Verwendung in Diagnostik oder Therapie.
Transport :
UN 1230, Class 3 (6.1), Packing group II
PubChem CID :
SMILES :
CC(=CCC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)C.N.N.N

SDS (MSDS) herunterladen

Analysenzertifikat

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