Molecular structure of Aldox, CAS Number: 45267-19-4
Aldox (CAS 45267-19-4)
Alternate Names:
MAPD; Schercodine M; Myristamidopropyl Dimethylamine
Application:
Aldox is an amidoamine compound that shows activity against Acanthamoeba
CAS Number:
45267-19-4
Molecular Weight:
312.53
Molecular Formula:
C19H40N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Aldox is an amidoamine compound that shows activity against Acanthamoeba as well as a variety of other causal agents of microbial keratitis. Aldox is a versatile antimicrobial agent that exhibits a wide spectrum of activity against bacteria, fungi, and protozoa. It is widely employed as a disinfectant in various settings, including hospitals, the food industry, and public spaces. Aldox demonstrates effectiveness against both Gram-positive and Gram-negative organisms, including amoebae and tissue cultures. While the precise mechanism of action of Aldox is not completely elucidated, it is believed to involve the disturbance of cell membranes through the activity of cationic surfactants like benzalkonium chloride
Aldox (CAS 45267-19-4) References
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- Aspects of the antimicrobial mechanisms of action of a polyquaternium and an amidoamine. | Codling, CE., et al. 2003. J Antimicrob Chemother. 51: 1153-8. PMID: 12697638
- Efficacy of myristamidopropyl dimethylamine (Aldox) against corneal isolates of Acanthamoeba spp. | Schuster, FL., et al. 2003. J Eukaryot Microbiol. 50 Suppl: 520-1. PMID: 14736149
- Anatomy of a regimen: consideration of multipurpose solutions during non-compliant use. | Rosenthal, RA., et al. 2003. Cont Lens Anterior Eye. 26: 17-26. PMID: 16303493
- Comparative cytotoxicity potential of soft contact lens care products. | Wright, A. and Mowrey-McKee, M. 2005. Cutan Ocul Toxicol. 24: 53-64. PMID: 17040888
- Contact lens solution efficacy against Acanthamoeba castellani. | Mowrey-McKee, M. and George, M. 2007. Eye Contact Lens. 33: 211-5. PMID: 17873623
- Lipophilic versus hydrodynamic modes of uptake and release by contact lenses of active entities used in multipurpose solutions. | Powell, CH., et al. 2010. Cont Lens Anterior Eye. 33: 9-18. PMID: 20034842
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- Microbial contamination of contact lens care accessories and compliance with care regimens in Nepal. | Panthi, S., et al. 2014. Cont Lens Anterior Eye. 37: 2-10. PMID: 23916116
- Antimicrobial Efficacy of Multipurpose Disinfecting Solutions in the Presence of Contact Lenses and Lens Cases. | Gabriel, MM., et al. 2018. Eye Contact Lens. 44: 125-131. PMID: 27598555
- Aldoxorubicin and Temozolomide combination in a xenograft mice model of human glioblastoma. | Da Ros, M., et al. 2018. Oncotarget. 9: 34935-34944. PMID: 30405885
- Analysis of Aldoxn alleles isolated from natural populations of Drosophila melanogaster. | Bentley, MM. 1986. Biochem Genet. 24: 291-308. PMID: 3089216
- Susceptibility of Contact Lens-Related Pseudomonas aeruginosa Keratitis Isolates to Multipurpose Disinfecting Solutions, Disinfectants, and Antibiotics. | Khan, M., et al. 2020. Transl Vis Sci Technol. 9: 2. PMID: 32821474
- Complete Recovery of Acanthamoeba Motility among Surviving Organisms after Contact Lens Care Disinfection. | Campolo, A., et al. 2023. Microorganisms. 11: PMID: 36838263
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aldox, 1 g | sc-396163 | 1 g | $425.00 | |||
Aldox, 100 g | sc-396163A | 100 g | $26600.00 |