ZDHHC16 Activators
ZDHHC16 activators represent a class of chemical compounds designed to modulate the activity of the enzyme ZDHHC16, also known as DHHC16 (Palmitoyltransferase ZDHHC16). ZDHHC16 is a member of the DHHC family of palmitoyltransferases, which are responsible for the post-translational modification of proteins through the attachment of lipid molecules, such as palmitate, to specific cysteine residues. This modification, known as palmitoylation, plays a critical role in regulating protein localization, stability, and function within cells.
ZDHHC16 activators are engineered to interact with ZDHHC16 and potentially influence its enzymatic activity. By targeting ZDHHC16, these compounds may affect the palmitoylation of specific target proteins, modulating their cellular properties and functions. Since palmitoylation is involved in a wide range of cellular processes, including signal transduction, membrane trafficking, and protein-protein interactions, the study of ZDHHC16 activators provides insights into the intricate mechanisms of post-translational protein modification and its consequences for cellular physiology. Understanding the regulation of palmitoylation by ZDHHC16 and its activators contributes to our knowledge of the diverse roles that lipid modifications play in the modulation of protein function and cellular processes. Further research is needed to uncover the specific mechanisms of action and biological implications associated with ZDHHC16 activation in various cellular contexts.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, raising cAMP levels, which can influence various gene expressions, possibly including ZDHHC16. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can influence various signaling pathways, potentially affecting the expression of ZDHHC16. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor. By affecting DNA methylation, it can potentially influence the expression of various genes, possibly including ZDHHC16. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid affects cellular differentiation. It might influence the expression of proteins involved in post-translational modifications, including ZDHHC16. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 is a proteasome inhibitor, influencing protein degradation pathways. This might affect the balance of protein modifications and influence ZDHHC16 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is known to modulate several signaling pathways and might indirectly influence the expression of proteins involved in palmitoylation, including ZDHHC16. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences various cellular pathways, including GSK-3β inhibition. This might modulate the expression of proteins related to post-translational modifications, like ZDHHC16. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a glucocorticoid, can modulate gene expression. Its effects on ZDHHC16 would be context-dependent. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin causes ER stress by inhibiting the ER calcium pump. ER stress might influence the expression of proteins related to protein modification, including ZDHHC16. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin affects multiple cellular pathways, potentially influencing the expression of proteins involved in post-translational modifications, like ZDHHC16. | ||||||